FILE - This Thursday, March 18, 2021 file photo shows syringes filled with the Moderna COVID-19 vaccine at a pop up site in the Queens borough of New York. According to results released on Monday, March 29, 2021, The U.S government’s first look at the real-world use of COVID-19 vaccines found their effectiveness was nearly as robust as it was in controlled studies. (AP Photo/Mary Altaffer)

FILE - This Thursday, March 18, 2021 file photo shows syringes filled with the Moderna COVID-19 vaccine at a pop up site in the Queens borough of New York. According to results released on Monday, March 29, 2021, The U.S government’s first look at the real-world use of COVID-19 vaccines found their effectiveness was nearly as robust as it was in controlled studies. (AP Photo/Mary Altaffer)

COVID vaccine found highly effective in real-world U.S. study

The two vaccines available since December — Pfizer and Moderna — were highly effective at 90% after two doses,

The U.S. government’s first look at the real-world use of COVID-19 vaccines found their effectiveness was nearly as robust as it was in controlled studies.

The two vaccines available since December — Pfizer and Moderna — were highly effective at 90% after two doses, the Centers for Disease Control and Prevention reported Monday. In testing, the vaccines were about 95% effective in preventing COVID-19.

“This is very reassuring news,” said the CDC’s Mark Thompson, the study’s lead author. “We have a vaccine that’s working very well.”

The study is the government’s first assessment of how the shots have been working beyond the drugmakers’ initial experiments. Results can sometimes change when vaccines are used in larger, more diverse populations outside studies.

With nearly 4,000 participants from six states, the study focused on health care workers, first responders and other front-line workers who had first priority for the shots because they are at higher risk. They were given nasal swab test kits to use every week to check for signs of a coronavirus infection.

“The evidence base for (currently available) COVID-19 vaccines is already strong, and continues to mount ever higher with studies like this one,” said David Holtgrave, dean of the University at Albany’s School of Public Health, in an email.

The study included roughly 2,500 volunteers who had completed two vaccine doses, about 500 who got one dose and about 1,000 who did not get vaccinated between mid-December and mid-March.

The researchers counted 205 infections, with 161 of them in the unvaccinated group. Of the remaining 44, the CDC said 33 of them were in people apparently infected within two weeks of a shot. Experts say it takes two weeks before a dose takes full effect.

No one died, and only two were hospitalized. Thompson did not say whether the people hospitalized were vaccinated or not.

Besides the 90% figure for two doses, the study found it was 80% effective for participants two weeks or more after a first dose.

CDC Director Dr. Rochelle Walensky called the study’s findings “tremendously encouraging.”

“Our national vaccination efforts are working,” she said during a White House press briefing Monday. She added that over 93 million Americans have received at least one vaccine dose and over 51 million people have been fully vaccinated.

Different researchers have tried to look at how the vaccines have performed in real-life conditions, including work done in Israel and the United Kingdom, and a U.S. study of Mayo Clinic patients.

Unlike the Mayo study, which focused on hospitalization and death, the CDC study looked for any infection — including infections that never resulted in symptoms, or were detected before people started feeling sick.

About two-thirds of the vaccinations in the study were Pfizer shots, one-third were Moderna and five people got the newest single-dose shot from Johnson & Johnson. The study was done in Miami; Duluth, Minnesota; Portland, Oregon; Temple, Texas; Salt Lake City; and Phoenix and other areas in Arizona.

Moderna, meanwhile, announced Monday that it had shipped its 100 millionth dose to the U.S. government, meeting its pledge to supply that amount by the end of March. The company said it expects to meet its next deadlines, of delivering another 100 million doses by the end of May and its final 100 million by the end of July.

READ MORE: B.C.’s frontline worker vaccine program in flux as AstraZeneca use paused for under-55s

___

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.

Mike Stobbe, The Associated Press


Like us on Facebook and follow us on Twitter.

Want to support local journalism during the pandemic? Make a donation here.

Coronavirusvaccines

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Comox Strathcona Waste Management expects to go to tender this summer for the regional organics compost facility in Campbell River. File photo/Black Press
Comox Strathcona compost site should go to tender this summer

The regional organics facility is on target to open for the fall of 2022

WestJet in flight. Black Press file photo
Two COVID exposures on WestJet flight into Comox

The BC Centre for Disease Control has posted advisories for two separate… Continue reading

Photo by Marc Kitteringham, Campbell River Mirror
Busy day for Campbell River fire crews

Three incidents in rapid succession keep crews on their toes

New electric buses are coming to school districts. (Submitted photo)
New electric school buses will drive North Island forward

Travel on electric school buses is smoother, quieter, and healthier than traditional diesel buses

Destroyed window at Ministry of Social Development offices in Campbell River. Photo supplied by Campbell River RCMP
Police investigating arson in downtown Campbell River

Fire set at BC Employment and Assistance Office

(The Canadian Press)
Trudeau won’t say whether Canada supports patent waiver for COVID-19 vaccines

‘Canada is at the table to help find a solution’

RCMP are looking for information on an alleged shooting attempt near an elementary school in Smithers March 10. (Phil McLachlan/Capital News/Stock)
UPDATE: Man killed in brazen daylight shooting at Vancouver airport

Details about the police incident are still unknown

Pieces of nephrite jade are shown at a mine site in northwestern B.C. in July 2019. THE CANADIAN PRESS/HO-Tahltan Central Government MANDATORY CREDIT
Indigenous nation opposes jade mining in northwestern B.C.

B.C.’s Mines Act requires operators to prepare a plan to protect cultural heritage resources

The body of Brenda Ware, 35, was found along Highway 93 in Kootenay National Park on Thursday, May 6, 2021. (RCMP handout)
RCMP ask for tips after woman’s body found in Kootenay National Park

Brenda Ware was found along Highway 93 in the park, 54 kilometres north of the town of Radium

People pass the red hearts on the COVID-19 Memorial Wall mourning those who have died, opposite the Houses of Parliament on the Embankment in London, Wednesday, April 7, 2021. On May 3, the British government announced that only one person had died of COVID-19 in the previous 24 hours. THE CANADIAN PRESS/AP-Kirsty Wigglesworth
For a view of a COVID-19 future, Canadians should look across the pond

Britain, like Canada, is one of the only countries in the world to delay second doses for several months

Edmonton Oilers’ Connor McDavid (97) celebrates his 100th point this season with Leon Draisaitl (29) against the Vancouver Canucks during second period NHL action in Edmonton on Saturday, May 8, 2021.THE CANADIAN PRESS/Jason Franson
Edmonton superstar McDavid hits 100-point mark as Oilers edge Canucks 4-3

NHL scoring leader needs just 53 games to reach century mark

Nuns of Mother Teresa’s Missionaries of Charity, carry some of her relics during a vigil of prayer in preparation for the canonization of Mother Teresa in the St. John in Latheran Basilica at the Vatican, Friday, Sept. 2, 2016. In which city did she do much of her charitable work? (AP Photo/Gregorio Borgia)
QUIZ: How much do you know about these motherhood issues?

In honour of Mother’s Day, take this 10-question quiz

Most Read